My psychiatrist finally got back the organic acid test results from over a month ago–it’s one of those where you mail in the samples, and the lab took forever getting back to us. Apparently my results were weird, not what he expected. He thought there would be something wonky about my mitochondria, but that came back fine. However, my fatty acid metabolism was high, and I have intestinal bacterial overgrowth of both L. acidophilus and Clostridial species. Apparently the bacterial overgrowth may indicate that the probiotics I’m taking aren’t the best kind for me, and he had no idea what the fatty acid oxidation issue meant. He has to check with one of the lab’s doctors and get back to me.
My detoxification indicators were also really wacky–ammonia toxicity and chronic low glutathione levels. Glutathione is one of the major detoxification things (I’m good at technical terms, see?) in the body, so being low in it isn’t good. I looked it up on Wikipedia, since the last time I took biology was 2002, and it tells me that “every system in the body can be affected by the state of the glutathione system, especially the immune system, the nervous system, the gastrointestinal system and the lungs.” Interesting that these are the systems I’ve been having the most problems with.
In the good news column, my yeast/fungal levels are normal, which is a radical change. The last time I was tested, I was off-the-chart high in Candida, but the course of Nystatin and S. Boulardii seems to have knocked that down to normal. Hilariously, my energy production markers had “no abnormalities found.” Tell that to my inability to stand up for more than 20 minutes at a time.
I also saw my gastroenterologist. I am pleased to announce that I don’t have to have another colonoscopy (yet). He thinks the Lialda may actually be what’s causing my current problems–its side effects can look just like the symptoms of UC. So he’s taking me off it for a week, and next week I’ll call and let him know if it’s made any difference. I’m not convinced–I’ve been on the Lialda since I was diagnosed in May of last year and haven’t changed the dose in 6 months (I’m maxed out), and I’ve only been having worse symptoms since December. Usually a drug doesn’t start causing problems all of a sudden like that when you haven’t changed the dose or anything, but I’ll try and see if it does any good.
He’s also going to fight with the insurance company to try to get me a larger supply of Zofran for the nausea. I hope that works out because uggghhhhh. I feel nauseous almost all the time, but I put off taking the Zofran because I want to have some left if things get really bad. Apparently my insurance company keeps insisting that I should take Phenergan instead, but that can cause toxic megacolon in UC patients. “Mega” is a word you want associated with your lottery win, not with your colon. But I guess my insurance likes it–after all, if my colon explodes and kills me, then they don’t have to pay for my meds anymore. Thanks, guys.
Now that I’ve told you all the fun news about my intestines, I’m going to go distract myself by watching the State of the Union, livetweeting/Facebooking, and then yelling at the Republican responses afterward.